Nocturnal scratching is a significant burden for individuals with psoriasis, leading to sleep disruption, skin damage, and reduced quality of life. While existing solutions for wrist-worn actigraphy in atopic dermatitis show promise, their applicability to psoriasis needs further exploration. This mission seeks to consolidate current knowledge on the relevance of itch, scratch, quality of sleep, and downstream impact specifically in psoriasis.

 

Overall Goal:

Establish a well-defined Measurement Definition for nocturnal scratch in psoriasis within the DEEP Stack Model, informed by a structured literature review and expert insights.

 

Specific Objectives:

Consolidate Knowledge: Conduct a focused literature search to gather information on the relevance of itch, scratch, sleep quality, and their impact in psoriasis.

Map Findings: Organize the extracted information into the DEEP checklists, highlighting key concepts and relationships.

Curate Measurement Definition: Create a structured Measurement Definition within the DEEP catalog, capturing the essential elements of nocturnal scratch in psoriasis.

Identify Gaps: Perform a gap analysis to pinpoint areas where further research or validation is needed.

Update Strategy: Enhance the Digital Measure Strategy Framework for nocturnal scratch in psoriasis based on the mission findings.

 

Potential Benefits:

Clearer understanding of the clinical relevance and patient burden of nocturnal scratch in psoriasis.

Foundation for developing validated digital measures for nocturnal scratch assessment in psoriasis.

Streamlined development and regulatory pathways for digital health technologies targeting this condition.

 

Call for Collaboration:

This initiative invites active participation from:

Pharmaceutical companies with psoriasis therapies in their pipeline or portfolio.

Device manufacturers creating wearable sensors for nocturnal scratch or sleep assessment.

Academic Institutions: Researchers and institutions conducting clinical studies on psoriasis and sleep.

Patient Advocacy Groups focused on psoriasis.

Service providers offering expertise in areas like literature review, data curation, or regulatory strategy.

 

Ways of contributing to a DEEP collaboration mission:

Contributions can be in the form of funding, time & expertise, or prior work. DEEP's framework simplifies collaboration. Questions? Reach out via the DEEP website here.

 

If you have questions, or if your organization is interested in contributing, please reach out to us here: